Tumor Regression After Treatment With Lenvatinib in FGFR2-Mutated Ameloblastoma
نویسندگان
چکیده
منابع مشابه
Activating FGFR2-RAS-BRAF mutations in ameloblastoma.
PURPOSE Ameloblastoma is an odontogenic neoplasm whose overall mutational landscape has not been well characterized. We sought to characterize pathogenic mutations in ameloblastoma and their clinical and functional significance with an emphasis on the mitogen-activated protein kinase (MAPK) pathway. EXPERIMENTAL DESIGN A total of 84 ameloblastomas and 40 non-ameloblastoma odontogenic tumors w...
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Multimodal therapy concepts have been successfully implemented in the treatment of locally advanced gastrointestinal malignancies. The effects of neoadjuvant chemo- or radiochemotherapy such as scarry fibrosis or resorptive changes and inflammation can be determined by histopathological investigation of the subsequent resection specimen. Tumor regression grading (TRG) systems which aim to categ...
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ژورنال
عنوان ژورنال: JCO Precision Oncology
سال: 2020
ISSN: 2473-4284
DOI: 10.1200/po.20.00175